Ctck domain-containing protein

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August undefined, 2024

WebIn molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms a compact folded three-dimensional … WebMar 21, 2024 · Summary. Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal …

Ig-like domains: Evolution from simple interaction molecules to ... - PNAS

WebTPR containing peptides Hop. The Hop adaptor protein mediates the association of the molecular chaperones Hsp70 and Hsp90. It contains three 3-TPR repeats each with its own peptide-binding specificity. Its TPR1 domain is known to recognize the C-terminal of Hsp70 while TPR2 binds to the C-terminal of Hsp90. WebFurthermore, P-domains have been found as components of extracellular mosaic proteins including certain mucins, where they are thought to play a role either in protein-protein … smart factories consulting

Helical self-assembly of a mucin segment suggests an ... - PNAS

WebJul 12, 2012 · The CTCK domain. The CTCK dimer forms a tee-shaped base for the dimeric bouquet (Figure 4D). The long axes of the 2 VWF CTCK domain monomers are … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … smart factors

The Roles of CCCH Zinc-Finger Proteins in Plant Abiotic Stress ...

CTCK domain-containing protein - Pseudonaja textilis …

WebMar 20, 2014 · All contain sequence signatures for the long β-strands present in CTCK, all contain C5 and C6 in β5 that form the reciprocal inter-chain disulfides, all have C2 and … WebNLRP3. NLR family pyrin domain containing 3 (NLRP3) (previously known as NACHT, LRR and PYD domains-containing protein 3 [NALP3] and cryopyrin), is a protein that in humans is encoded by the NLRP3 gene [5] located on the long arm of chromosome 1. [6] NLRP3 is expressed predominantly in macrophages and as a component of the … smart facilitator trainingWebJul 12, 2012 · The work described herein builds on early, significant work on the determination of the protein sequence, disulfide connectivity, cDNA sequence, and … hilliglass electric

"WebAug 3, 2024 · Zinc-finger proteins, a superfamily of proteins with a typical structural domain that coordinates a zinc ion and binds nucleic acids, participate in the regulation … " - Ctck domain-containing protein

Ctck domain-containing protein

Highly reinforced structure of a C-terminal dimerization domain in …

WebDescription: Homo sapiens mucin 5AC, oligomeric mucus/gel-forming (MUC5AC), mRNA. (from RefSeq NM_001304359) Gencode Transcript: ENST00000621226.2 Gencode Gene ... WebThis protein is a glycoprotein of the α2 globulin fraction of the serum and contains 95% of the copper in the plasma (Hellman & Gitlin, 2002). Ceruloplasmin consists of a single …

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WebMay 15, 2024 · Previously, we demonstrated that a SAM domain-containing protein, SAMD14, promotes SCF/proto-oncogene c-Kit (c-Kit) signaling, erythroid progenitor function, and erythrocyte regeneration. Deletion of a Samd14 enhancer (Samd14-Enh), occupied by GATA2 and SCL/TAL1 transcription factors, reduces SAMD14 expression in …

WebMay 27, 2024 · The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Hsu DR, Economides AN, Wang X, Eimon PM, Harland RM. Mol Cell, (5):673-683 1998 MED: 9660951 ... CTCK domain-containing protein (UniProt - B3KTR9) Gremlin (UniProt - A6XAA7) Gremlin-1 (UniProt - O60565) … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. …

WebBone morphogenetic proteins (BMPs) are secreted growth factors that promote differentiation processes in embryogenesis and tissue development. Regulation of BMP signaling involves binding to a variety of extracellular proteins, among which are many von Willebrand factor C (vWC) domain-containing proteins. Although the crystal structure … http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00041

WebThe protein mass of MUC2 residues 1398 to 4331 (the PTS region containing the CysD2 domain) is about 295,000 g/mol. Using the v for proteins of 0.73 cm 3 /g, the protein …

WebCARD domains are a subclass of protein motif known as the death fold, which features an arrangement of six to seven antiparallel alpha helices with a hydrophobic core and an outer face composed of charged residues. Other motifs in this class include the pyrin domain (PYD), death domain (DD), and death effector domain (DED), all of which also ... smart factory 2023WebDec 1, 2013 · 4NT5. PubMed Abstract: The C-terminal cystine knot (CK) (CTCK) domain in von Willebrand factor (VWF) mediates dimerization of proVWF in the endoplasmic reticulum and is essential for long multimers required for hemostatic function. The CTCK dimer crystal structure reveals highly elongated monomers with 2 β-ribbons and 4 intra-chain disulfides ... hillig trailer long prairie mnWebApr 8, 2024 · TUDOR domain-containing protein 1, 4 and 5 are antigens expressed on testis cells and are hallmarks of cancer (Yoon et al., 2011). ... CT or CTCK (C-terminal … smart facilitator training ukWebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. [5] [6] CDCP1 has also been designated as CD318 ( cluster of … hillin and clarkWebMay 26, 2024 · The TBC1D23 protein functions in membrane trafficking and is critical for human neuronal development. The crystal structure of the N-terminus of TBC1D23 shows that its rhodanase domain is catalytically inactive and positioned close to the adjacent TBC domain, which together provide a binding interface for golgin-97/245. This interaction is … smart facial scanner analyzer supplierWebDec 21, 1999 · Blob diagram to illustrate various proteins containing IgSF domains, including the antigen receptors. The IgSF domains are illustrated by open circles and marked V, C1, or C2 according to sequence patterns and size . The lollipop symbols indicate the approximate position of N-linked glycosylation sites. The arrow in Thy-1 indicates the … hilligoss shrader obituariesWebMar 20, 2014 · VWF is a large (∼250 kDa) protein containing multiple domains (multicolored cylinders), including the CTCK domain (thin, light-colored disk) at one end … smart factor warszawa