Ctcf和ctcfl

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August undefined, 2024

WebFeb 1, 2014 · CTCF and BORIS in the genomic landscape. CTCF (CCCTC-binding factor) is a ubiquitous multivalent 11-zinc finger (ZF) protein that can bind tens of thousands of sites across the human genome depending on cell type [1, 2••, 3••, 4].CTCF was initially identified as a transcriptional regulator [5].It is now recognised as having diverse roles as an … Web我们为您找到 ctcf 的 1 个相关产品结果。 ... 生命科学基础与转化研究的主要领域，包括细胞生物学、肿瘤、免疫与炎症、表观遗传学和转录调控、代谢与内分泌、衰老、心血管、干细胞和发育、神经科学、蛋白质翻译后修饰等，还提供病理学研究与伴随诊断 ...

Early vertebrate origin of CTCFL, a CTCF paralog, revealed by …

WebSep 3, 2024 · The putative ORFs of these shark CTCFL genes, as well as their CTCF genes (Supplementary Data 1), were all revealed to possess eleven zing finger domains, as known for CTCF and CTCFL genes of ... WebApr 1, 2024 · CTCFL binds to a very similar sequence than CTCF and, if expressed at higher levels, as it does in many cancers, could compete with CTCF for binding at a subset of sites [51, 52]. Since CTCFL lacks the domain required for cohesin interaction, this protein is unable to stop cohesin extrusion and to form stable loops between distant sites in the ... the orrville

Choice of binding sites for CTCFL compared to CTCF is driven by ...

WebThe two paralogous zinc finger factors CTCF and CTCFL differ in expression such that CTCF is ubiquitously expressed, whereas CTCFL is found during spermatogenesis and … WebCTCFL Antibodies. Antibodies that detect CTCFL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, … WebJun 18, 2012 · CTCFL acts as a male germ cell gene regulator, preferably binding near promoters with active chromatin marks. Interestingly, CTCF and CTCFL bind a highly … shropshire triathlon course

Entry - *607022 - CCCTC-BINDING FACTOR-LIKE PROTEIN; CTCFL …

Defining the relative and combined contribution of CTCF …

WebCTCFL paralog; transcriptional repressor CTCF; Background Information: CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions. A transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers. WebOct 7, 2014 · Thus, the comparison between CTCF and CTCFL domains revealed that only CTCF harbours the powerful chromatin opening domain within the N-terminus plus zinc finger region. Chromatin opening is usually associated with, or is caused by, histone modifications. Since we found the closed array of the F42B8 cells to be devoid of active … the orsayWebU25435 - Human transcriptional repressor (CTCF) mRNA, complete cds. BC130486 - Homo sapiens CCCTC-binding factor (zinc finger protein)-like, mRNA (cDNA clone MGC:163358 IMAGE:40146517), complete cds. DQ294738 - Homo sapiens BORIS-like protein (CTCFL) mRNA, complete cds, alternatively spliced. BC014267 - Homo sapiens CCCTC-binding … the orry eaglesham

"WebCTCF formira izolatore osjetljive na metilaciju, koji reguliraju Inaktivaciju X-hromosoma. Transkripcijski potiskivač CTCFL (ovaj protein) je paralog CTCF-a i čini se da se prvenstveno eksprimira u citoplazmi spermatocit a, za razliku od CTCF-a, koji se primarno ispoljava u jedru somatskih ćelija. " - Ctcf和ctcfl

Ctcf和ctcfl

WebJan 5, 2024 · CCCTC-binding factor (CTCF) is a transcription factor that is involved in organizing chromatin structure. A reduction of CTCF expression is known to develop distinct clinical features. Furthermore, conditional knock out (cKO) study revealed reactive gliosis of astrocytes and microglia followed by age-dependent cell death in the excitatory neurons … WebCTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is normally transiently …

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WebCTCF常常位于TAD和loop的边界，起到“隔离子”的作用。近年来提出的loop extrusion模型也认为CTCF和cohesin的协调作用是loop形成的普遍机理。然而，虽然有了假设，人们却一直不清楚CTCF是如何作用于染色质，并 … WebCTCF-mediated enhancer blocking is conserved from Drosophila to man (Moon et al. 2005) Antisense transcription of triplet repeats is constrained by CTCF (Cho et al. 2005) Boundaries between X inactivation and escape of inactivation bind CTCF (Filippova et al. 2005) CTCF antagonizes with CTCFL at the cancer testis gene MAGE-A1 (Vatolin et al. …

WebSep 3, 2024 · Asymmetric expression patterns between shark CTCF and CTCFL. To examine possible commonalities of expression patterns with mammals, we analyzed … WebMay 11, 2024 · Ubiquitously expressed CTCF is involved in numerous cellular functions, such as organizing chromatin into TAD structures. In contrast, its paralog, CTCFL, is normally only present in the testis. However, it is also aberrantly expressed in many cancers. While it is known that shared and unique zinc finger sequences in CTCF and CTCFL …

WebApr 1, 2024 · CTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is … WebMay 11, 2024 · CTCFL and CTCF-CTCFL overlapping binding sites are frequently bound by both CLC and LCL (Fig. 4 d, e), but at some locations, fusion protein peaks are reduced in size compared to that of CTCFL (e.g., at Ctcfl, Prss50, Gal3st1 loci) (Fig. 4 d). Sites bound by CTCF only were preferentially bound by LCL as opposed to CLC (Fig. 4 f).

Web5.1 CTCF genome organizer and the cohesin complex. CTCF (CCCTC-binding factor) is a multiple zinc finger protein that exerts diversified functions under different genomic …

WebAnti-CTCF Antibody serum, Upstate®; Synonyms: 11 zinc finger transcriptional repressor, 11-zinc finger protein, CCCTC-binding factor, CCCTC-binding factor (zinc finger protein), CTCFL paralog, transcriptional repressor CTCF; find Sigma-Aldrich-07729 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich shropshire trout fishingWeb5.1 CTCF genome organizer and the cohesin complex. CTCF (CCCTC-binding factor) is a multiple zinc finger protein that exerts diversified functions under different genomic contexts. CTCF was first isolated and cloned on the basis of its ability to bind to highly divergent 50–60 bp sequences within the promoter region of the chicken Myc gene ... shropshire truck \u0026 trailer partsWebWidespread expression of BORIS/CTCFL in normal and cancer cells. BORIS (CTCFL) is the paralog of CTCF (CCCTC-binding factor; NM_006565), a ubiquitously expressed … shropshire trophy centreWebNov 30, 2010 · Function. Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by … shropshire truck \u0026 trailer parts limitedWebFeb 7, 2024 · In this case, we also found previously validated targets of CTCFL (Supplementary Fig. 3a, b), such as TGFB1 31, FN1 7, and the H19 gene, which has been widely studied as a target of CTCFL and CTCF ... the orsay museumWebChIPAb+ CTCF - ChIP Validated Antibody and Primer Set clone 1.2.1.5.4, from mouse; Synonyms: 11 zinc finger transcriptional repressor, 11-zinc finger protein, CCCTC-binding factor, CCCTC-binding factor (zinc finger protein), CTCFL paralog, transcriptional repressor CTCF; find Sigma-Aldrich-1710044 MSDS, related peer-reviewed papers, technical … the orsen fundWebMar 29, 2024 · CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapy. Transcription Factor CTCFL Promotes Cell Proliferation, … shropshire truck and trailer