WebAim: To clarify laboratory guidelines for cerebrospinal fluid (CSF) cytology. Methods: Clinical and pathological data relating to 54 patients with cytologically malignant cells in the CSF were reviewed, together with CSF cell counts and protein measurements for 29 patients. Utilising this data, criteria were established for CSF cytology and validated by … Web2 days ago · Leptomeningeal metastasis (LM) refers to the spread of malignant cells to the leptomeninges, subarachnoid space, and other cerebrospinal fluid (CSF) compartments [].LM is a devastating complication that occurs in 3–5% of patients with advanced non-small cell lung cancer (NSCLC) [].However, its incidence is higher in subgroups of patients …
Comprehensive RNA analysis of CSF reveals a role for CEACAM6
WebApr 1, 2024 · Cerebrospinal fluid (CSF) analysis is a diagnostic tool for many conditions affecting the central nervous system. Urgent indications for lumbar puncture include suspected central nervous system ... WebMay 26, 2012 · Cytological analysis is considered the gold standard for the identification of malignant cells in the CSF . The benefits of cytology in the identification of malignant cells in CSF were first reported in 1904 . Subsequently, many publications supported this finding [12–14]. CSF analysis quickly gained popularity in the identification of CNS ... ipr people
CSF and laboratory analysis (tumor markers) - ScienceDirect
WebCytology should be performed on cerebrospinal specimens from all patients with known or suspected malignancy with meningismus. Detection of malignant cells on cytological examination of CSF is the diagnostic gold standard for neoplastic meningitis. WebHowever, pathologists often report CSF cytology results as “suggestive of malignant cells” or “atypical cells present”. Radiologists often report MRI finding as “suspicious” or “equivocal” for LM. LM is frequently asymptomatic despite definite MRI … WebAug 4, 2014 · These 10 patients had a total of 40 CSF cytology specimens available that were collected as part of their treatment protocol, and that were interpreted as positive for malignant cells. ... (80%) were either highly (16 cases) or moderately (16 cases) cellular. The malignant cells varied in size from 13.3 μm to 63.3 μm, representing small (4 ... ipr patent schedule